Synonyms	GARP;GARPGarpin;Garpin;D11S833E
Species	Human
Expression_host	HEK293 Cells
Sequence	His20-Asn627
Accession	Q14392
Mol_Mass	92.9 kDa
AP_Mol_Mass	110 kDa
Tag	C-Fc

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress na?ve T cell proliferation. LRRC32 is widely expressed during embryogenesis and on adult platelets. Human LRRC32 is identified as a lineage specific key receptor for human T cells.

Citations

Reviews/Q&A

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Q&A

Y********uSubmitted [ May 01 2023 ]

Asked: Hello! I was wondering how long does it take for delivering to the Netherlands?

adminSubmitted [ May 01 2023 ]

Answered: Hi Yanzhe, for transportation, it takes 5-7 days t oarrive in the NL. As to the lead time, it depends on the size and quantity you order. We will keep talking by email. Have a nice day!

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