Synonyms	Methionine Aminopeptidase 1D Mitochondrial;Methionyl Aminopeptidase Type 1D Mitochondrial;METAP1D;MAP1D;MAP 1D;MetAP 1D;Metap1l
Species	Human
Expression_host	E.coli
Sequence	Arg44-Ala335
Accession	Q6UB28
Mol_Mass	35.4 kDa
AP_Mol_Mass	35-40 kDa
Tag	N-His & C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.
Reconstitution	Not Applicable

Background

Methionine Aminopeptidase 1D (METAP1D) is a mitochondrion protein that belongs to the peptidase M24A family. METAP1D is overexpressed at the protein level in colon cancer cell lines and colon tumors as compared to normal tissues. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. METAP1D is also active with zinc, manganese or divalent ions. It may also play an important role in colon tumorigenesis.

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