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Recombinant Human METAP1 Protein

    • Recombinant Human METAP1 Protein-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human METAP1 Protein-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human METAP1 Protein-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033589

      Synonyms:Methionine aminopeptidase 1; MAP 1; MetAP 1; Peptidase M 1; METAP1;MAP1A;MetAP1A

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $263

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      Overview

      Synonyms Methionine aminopeptidase 1; MAP 1; MetAP 1; Peptidase M 1; METAP1;MAP1A;MetAP1A
      Species Human
      Expression_host E.coli
      Sequence Met1-Phe386
      Accession P53582
      Mol_Mass 43.2 kDa
      AP_Mol_Mass 38&45-50 kDa

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris,500mM NaCl,10%glycerol,pH8.0.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Methionine Aminopeptidase 1 is a member of the M24 family of metalloproteases. METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. Inhibition of METAPs provides a novel strategy in developing anti-cancer drugs.

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      MSDS for ELISA ISO 9001

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