Recombinant Human MMP-3 Protein (His Tag)

    • Recombinant Human MMP-3 / Matrix metalloproteinase-3 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human MMP-3 / Matrix metalloproteinase-3 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human MMP-3 / Matrix metalloproteinase-3 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033591

      Synonyms:Stromelysin-1; SL-1; Matrix metalloproteinase-3;Transin-1; MMP3; STMY1;CHDS6;MMP-3;SL-1;STMY;STR1

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $328

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Stromelysin-1; SL-1; Matrix metalloproteinase-3;Transin-1; MMP3; STMY1;CHDS6;MMP-3;SL-1;STMY;STR1
      Species Human
      Expression_host Human Cells
      Sequence Tyr18-Cys477(Lys45Glu)
      Accession P08254
      Mol_Mass 53.26 kDa
      AP_Mol_Mass 52 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, 0.05% Brij35, 10% Glycerol, pH 7.5.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.

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