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Recombinant Human/Mouse/Rat BMP-2 Protein

Uniprot : P12643
  • Cat.No.:PKSR030454

  • Expression host: E.coli

To Purchase PKSR030454

Size:
  • 20μg
  • 100μg
Price: $249
Qty:

Description

Synonyms Bone Morphogenetic Protein 2;BMP-2;Bone Morphogenetic Protein 2A;BMP-2A;BMP2;BMP2A
Species Human/Mouse/Rat
Expression_host E.coli
Sequence Gln283-Arg396
Accession P12643
Mol_Mass 13.8 kDa
AP_Mol_Mass 14 kDa
Tag C-His
Bio_Activity Measure by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED50 for this effect is <1.0 μg/mL.

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 0.1 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.

Background

Bone Morphogenetic Protein-2 (BMP-2) is one of the bone-growth regulatory factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of proteins. BMPs are synthesized as large precursor molecules, which are cleaved by proteolytic enzymes. The active form of BMP-2 can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.

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