Recombinant Human NACHRA5/CHRNA5 Protein (His Tag)

    • Recombinant Protein-Elabscience
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    • Recombinant Protein-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033582

      Synonyms:Neuronal Acetylcholine Receptor Subunit Alpha-5; CHRNA5; NACHRA5

      Size:
      • 10μg
      • 50μg
      Qty:
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      Price: $178

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      Overview

      Synonyms Neuronal Acetylcholine Receptor Subunit Alpha-5; CHRNA5; NACHRA5
      Species Human
      Expression_host Human Cells
      Sequence Arg23-Thr254
      Accession P30532
      Mol_Mass 27.6 kDa
      AP_Mol_Mass 35-40 kDa
      Tag C-His

      Properties

      Purity > 90% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Neuronal Acetylcholine Receptor Subunit α-5 (NACHRA5) is a member of the ligand-gated ion channel family. Neuronal AChR is composed of two different type of subunits: α and non-α. When NACHRA5 binds to acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits, leading to the opening of an ion-conducting channel across the plasma membrane. Genetic variations in NACHRA5 have been related to susceptibility to smoking-related behavioral traits and lung cancer, contributing to the smoking quantitative trait locus 3.
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      MSDS for ELISA ISO 9001

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