Synonyms	Adaptin ear-binding coat-associated protein 2;NECAP endocytosis associated protein 2;NECAP2
Species	Human
Expression_host	E.coli
Sequence	Met 1-Phe263
Accession	Q9NVZ3
Mol_Mass	31.5 kDa
AP_Mol_Mass	35 kDa
Tag	N-His & C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of PBS, 2mM EDTA, 1mM DTT, pH 7.4.
Reconstitution	Not Applicable

Background

NECAP2 belongs to the NECAP family. The WXXF motifs mediate binding of accessory proteins to the ear-domain of AP-1, GGAs and AP-2 through hydrophobic interactions. Adaptin ear-binding coat-associated protein 2 can interacts with AP1G1 and AP2A1 components of the adapter protein complex AP-1 and AP-2. It also interacts with the GAE domain proteins GGA1, GGA2 and GGA3.

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