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Recombinant Human Neuroplastin/NPTN Protein (His Tag)

Uniprot : Q9Y639
  • Cat.No.:PKSH032801

  • Expression host: HEK293 Cells

To Purchase PKSH032801

Size:
  • 10μg
  • 50μg
Price: $129
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Description

Synonyms Neuroplastin;Stromal Cell-Derived Receptor 1;SDR-1;NPTN;SDFR1;SDR1
Species Human
Expression_host HEK293 Cells
Sequence Gln29-His220
Accession Q9Y639
Mol_Mass 22.7 kDa
AP_Mol_Mass 35-55 kDa
Tag C-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed man
Reconstitution Please refer to the printed manual for detailed information.

Background

Neuroplastin (NPTN) is a 52-57 kDa member of the Ig-superfamily. Neuroplastin likely serves as a cell adhesion molecule, and is widely expressed in multiple tissues. Human Neuroplastin is 282 amino acids that contions two Ig-like domains and a 38 aa cytoplasmic region. Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. Neuroplastin may also regulate neurite outgrowth by activating the FGFR1 signaling pathway. It may play a role in synaptic plasticity.

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