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Recombinant Human NLGN4X Protein (His Tag)

Uniprot : Q8N0W4
  • Cat.No.:PKSH032797

  • Expression host: HEK293 Cells

To Purchase PKSH032797

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  • 10μg
  • 50μg
Price: $129
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Description

Synonyms Neuroligin-4 X-Linked;Neuroligin X;HNLX;NLGN4X;KIAA1260;NLGN4
Species Human
Expression_host HEK293 Cells
Sequence Gln42-Ser676
Accession Q8N0W4
Mol_Mass 72.5 kDa
AP_Mol_Mass 95 kDa
Tag C-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual
Reconstitution Please refer to the printed manual for detailed information.

Background

Neuroligin 4, X-Linked (NLGN4X) is a single-pass type I membrane protein that belongs to the type-B carboxylesterase/lipase family. NLGN4X is detected at higher levels in heart and at lower levels in the liver, skeletal muscle, and pancreas. NLGN4X is a putative neuronal cell surface protein involved in cell-cell-interactions. NLGN4X may act as splice site-specific ligands for β-neurexins. It has been shown that NLGN4X is involved in the formation and remodeling of central nervous system synapses. NLGN4X also interacts with discs, large (Drosophila) homolog 4 (DLG4). Defects in NLGN4X have been associated with autism and Asperger syndrome.

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