Recombinant Human OX40/TNFRSF4 Protein (Fc & Avi Tag)

    • Recombinant Human OX40 / TNFRSF4 Protein (C-Fc-Avi)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human OX40 / TNFRSF4 Protein (C-Fc-Avi)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human OX40 / TNFRSF4 Protein (C-Fc-Avi)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033797

      Synonyms:Recombinant Human OX40/TNFRSF4 Protein (C-Fc-Avi)

      Size:
      • 20μg
      • 100μg
      Qty:
      - +
      Price: $342

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Recombinant Human OX40/TNFRSF4 Protein (C-Fc-Avi)
      Species Human
      Expression_host Human Cells
      Sequence Leu29-Ala216
      Accession P43489
      Mol_Mass 48.6 kDa
      AP_Mol_Mass 60-85 kDa
      Tag C-Fc-Avi

      Properties

      Purity > 90% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.

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