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Recombinant Human Parathyroid Hormone/PTH Protein (1-84)

Uniprot : P01270

Cat.No.:PKSH032854
Expression host: E.coli

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Description

Synonyms	Parathyroid Hormone;PTH;Parathormone;Parathyrin;PTH1
Species	Human
Expression_host	E.coli
Sequence	Ser32-Gln115
Accession	P01270
Mol_Mass	9.4 kDa
AP_Mol_Mass	14 kDa
Tag	None

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 5% Mannitol, pH 4.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information
Reconstitution	Please refer to the printed manual for detailed information.

Background

Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone; parathyroid hormone-related protein; binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones; parathyroid hormone is synthesized as a preprohormone. After intracellular processing; the mature hormone is packaged within the Golgi into secretory vesicles; the secreted into blood by exocytosis. Parathyroid hormone is secreted as a linear protein of 84 amino acids.

Citations

Reviews/Q&A

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Q&A

R******** Submitted [ Apr 19 2024 ]

Asked: What is the concentration of the product? We currently have the 50-microgram pack.

adminSubmitted [ Apr 19 2024 ]

Answered: Hello Rituparna.We will reply you via E-mail.

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