Recombinant Human PDGFRa/CD140a Protein (His Tag)

    • Recombinant Human PDGFRa / CD140a Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human PDGFRa / CD140a Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human PDGFRa / CD140a Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033564

      Synonyms:CD140A;PDGFR-2;PDGFR2;RHEPDGFRA;Platelet-derived growth factor receptor alpha; PDGFR-alpha; Alpha platelet-derived growth factor receptor;CD140 antigen-like family member A; Platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $92

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms CD140A;PDGFR-2;PDGFR2;RHEPDGFRA;Platelet-derived growth factor receptor alpha; PDGFR-alpha; Alpha platelet-derived growth factor receptor;CD140 antigen-like family member A; Platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2
      Species Human
      Expression_host Human Cells
      Sequence Gln24-Glu524
      Accession P16234
      Mol_Mass 57 kDa
      AP_Mol_Mass 93 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Platelet-derived Growth Factor Receptor Alpha (PDGF Rα) is an enzyme that belongs to the class III subfamily of receptor tyrosine kinases.It is a type I transmembrane glycoprotein, and can form homo- or hetero-dimeric receptors when engaged by dimers of the PDGF family of growth factors, PDGF Rα is strongly expressed in oligodendrocyte, lung, skin and intestinal progenitor cells and induced by inflammation or growth in culture, but is lowly expressed in most mesenchymal cells. PDGF Rα autophosphorylates upon dimerization, activating signaling cascades in PI-3kinase Ras-MAP kinase, and PLC-γ pathways. PDGF Rα has infulence on local gradients of epithelially produced PDGF-AA or PDGF-CC during formation of the cranial ,cardiac neural crest and interstitial kidney mesenchyme.

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      MSDS for ELISA ISO 9001

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