Recombinant Human Peroxiredoxin 6/PRDX6 Protein (His Tag)

acid phosphatase-like protein 2; also known as ACPL2; is a secreted protein which belongs to thehistidine acid phosphatase family. A large-scale effort; termed the Secreted Protein Discovery Initiative (SPDI); was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches; a biological signal sequence trap in yeast cells was utilized to identify cDNA clones encoding putative secreted proteins. A second strategy utilized various algorithms that recognize features such as the hydrophobic properties of signal sequences to identify putative proteins encoded by expressed sequence tags (ESTs) from human cDNA libraries. A third approach surveyed ESTs for protein sequence similarity to a set of known receptors and their ligands with the BLAST algorithm. Finally; both signal-sequence prediction algorithms and BLAST were used to identify single exons of potential genes from within human genomic sequence.