Synonyms	Phosphatidylinositol Transfer Protein Alpha Isoform;PI-TP-Alpha;PtdIns Transfer Protein Alpha;PtdInsTP Alpha;PITPNA;PITPN
Species	Human
Expression_host	E.coli
Sequence	Met 1-Asp270
Accession	Q00169
Mol_Mass	34.0 kDa
AP_Mol_Mass	16&22&38 kDa
Tag	N-His

Properties

Purity	> 90 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM EDTA, 1mM DTT, pH 8.0.
Reconstitution	Not Applicable

Background

Phosphatidylinositol Transfer Protein α Isoform (PITPNA) is found in the cytoplasm and belongs to the PtdIns transfer protein family. PITPNA is a ubiquitous and highly conserved protein in multicellular eukaryotes that catalyzes the exchange of phospholipids between membranes and participates in cellular phospholipid metabolism, signal transduction and vesicular trafficking in vivo. It is expressed in a wide range of tissues and implicated in phospholipase C signaling and in the production of phosphatidylinositol 3, 4, 5-trisphosphate (PIP3) by phosphoinositide-3-kinase.

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