Synonyms	Group XVI Phospholipase A1/A2;Adipose-Specific Phospholipase A2;AdPLA;H-Rev 107 Protein Homolog;HRAS-Like Suppressor 1;HRAS-Like Suppressor 3;HRSL3;HREV107-1;HREV107-3;Renal Carcinoma Antigen NY-REN-65;PLA2G16;HRASLS3;HREV107
Species	Human
Expression_host	E.coli
Sequence	Asp12-Asp132
Accession	P53816
Mol_Mass	14-17 kDa
AP_Mol_Mass	15 kDa
Tag	N-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50mM NaCl, 1mM EDTA, pH8.0.
Reconstitution	Not Applicable

Background

Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models.

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