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Recombinant Human Placental Alkaline Phosphatase 1/ALPP Protein (His Tag)

Uniprot : P05187

Cat.No.:PKSH032058
Expression host: HEK293 Cells

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Description

Synonyms	Alkaline phosphatase;placental type;Alkaline phosphatase Regan isozyme;Placental alkaline phosphatase 1;ALPP and PLAP;
Species	Human
Expression_host	HEK293 Cells
Sequence	Ile23-Asp506
Accession	P05187
Mol_Mass	53.7 kDa
AP_Mol_Mass	60-85 kDa
Tag	C-His
Bio_Activity	Not validated for activity

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.2mM CaCl₂, 10% Glycerol, pH 7.5.
Reconstitution	Not Applicable

Background

ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a role in a number of processes including cell signaling, long-term potentiation, and cell adhesion, however, the best known and most commonly studied role is implicated in Alzheimer's research.

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