Synonyms	Bone Marrow Proteoglycan;BMPG;Proteoglycan 2;Eosinophil Granule Major Basic Protein;EMBP;MBP;Pregnancy-Associated Major Basic Protein;PRG2;MBP
Species	Human
Expression_host	HEK293 Cells
Sequence	Leu17-Tyr222
Accession	AAH05929.1
Mol_Mass	24.6 kDa
AP_Mol_Mass	33 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution	Not Applicable

Background

Bone Marrow Proteoglycan (BMPG) is a secreted protein that contains one C-type lectin domain. BMPG is the predominant constituent of the crystalline core of the eosinophil granule. BMPG is highly expressed in placenta and pregnancy serum. BMPG may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin. BMPG induces non-cytolytic histamine release from human basophils. In addition, BMPG also participated in antiparasitic defense mechanisms and immune hypersensitivity reactions.

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