English Toll-free:1-888-852-8623 or Contact Us
Keyword cannot be empty !

Recombinant Human PSMA Protein (His Tag)

Cat:PKSH033667
Manual MSDS

Price: $ 593

Price: $ 223

Size:
50μg 10μg
Quantity:
  • Expression Host: HEK293 Cells
  • Accession: Q04609
Add to cart

For research use only. Order now, ship in 3 days

Product Details
Synonyms Glutamate carboxypeptidase 2;FGCP;GCPII;mGCP;NAALADase I;PSMA;Cell growth-inhibiting gene 27 protein;Folate hydrolase 1;FOLH1;GCP2;FGCP;GCPII;Mgcp;NAALADase I;FOLH;mGCP;NAALAD1;NAALAdase;PSM;PSMA
Species Human
Expression Host HEK293 Cells
Sequence Lys44-Ala750
Accession Q04609
Calculated Molecular Weight 80.6 kDa
Observed Molecular Weight 90-120 kDa
Tag N-His
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, 5% Trehalose, pH 5.5.
Reconstitution Not Applicable
Background Glutamate carboxypeptidase 2, also known as FOLH1, PSMA, belongs to the M28B subfamily and the peptidase M28 family. It is highly expressed in prostate epithelium and can be detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). PSMA is used as a diagnostic and prognostic indicator of prostate cancer, and as a possible marker for various neurological disorders such as schizophrenia, Alzheimer disease and Huntington disease. It has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity and has a preference for tri-alpha-glutamate peptides. PSMA involves in prostate tumor progression and also exhibits a dipeptidyl-peptidase IV type activity. In vitro, PSMA cleaves Gly-Pro-AMC. PSMA is stable at pH greater than 6.5.