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Recombinant Human RCN2 (C-6His)

Uniprot : Q14257
  • Cat.No.:PKSH034035

  • Expression host: Human Cells

To Purchase PKSH034035

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  • 10µg
  • 50µg
Price: $220
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Description

Synonyms Reticulocalbin-2; RCN2; E6BP; ERC55
Species Human
Expression_host Human Cells
Sequence Gly23-Leu317
Accession Q14257
Mol_Mass 35.6 kDa
AP_Mol_Mass 50-55 kDa
Tag C-6His

Properties

Purity >95% as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per µg as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt,store it immediately at<-20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, 1mM DTT, pH 8.0.
Reconstitution Please refer to the printed manual for detailed information.

Background

Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, the family members could play oncogenic roles in human malignancies and facilitate tumor cell proliferation and metastasis. Recently, studies on RCN2 functions mainly focused on its role in differentiation and endocrine regulation in mouse. Another study has suggested that RCN2 could be a potential tumor-associated antigen for mammary cancer immunological prevention. Up to now, the experimental evidence uncovering the role of RCN2 in cancer is very limited.

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