Recombinant Human ROR2 Protein (His Tag)

    • Recombinant Human ROR2 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human ROR2 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human ROR2 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033479

      Synonyms:Tyrosine-protein kinase transmembrane receptor ROR2; Neurotrophic tyrosine kinase, receptor-related 2; ROR2; NTRKR2

      Size:
      • 10μg
      • 50μg
      Qty:
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      Price: $111

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      Overview

      Synonyms Tyrosine-protein kinase transmembrane receptor ROR2; Neurotrophic tyrosine kinase, receptor-related 2; ROR2; NTRKR2
      Species Human
      Expression_host Human Cells
      Sequence Glu34-Gly403
      Accession Q01974
      Mol_Mass 42.2 kDa
      AP_Mol_Mass 50-60 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Receptor Tyrosine Kinaselike Orphan Receptor 2(ROR2) belongs to the protein kinase superfamily, Tyr protein kinase family and ROR subfamily. It is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. ROR2 promotes osteogenesis, binds YWHAB and Interacts with WTIP. ROR2 is broadly expressed during embryonic development and can be found in cells of all three germ layers as well as in most organ tissues. Activation of ROR2 signaling promotes cellular proliferation, differentiation, cellpolarization, and migration. ROR2 has also been shown to have very little tyrosine kinase activity in vitro and may act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling.

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