Synonyms	S100A6;Protein S100-A6;Calcyclin;Growth factor-inducible protein 2A9;MLN 4;Prolactin receptor-associated protein;PRA;S100 calcium-binding protein A6;CACY;2A9;5B10;CABP;PRA
Species	Human
Expression_host	E.coli
Sequence	Met 1-Gly 90
Accession	NP_055439.1
Mol_Mass	10.2 kDa
AP_Mol_Mass	10 kDa
Tag	None

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from sterile PBS, pH 7.4 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

S100 proteinis a family of low molecular weight protein found in vertebrates characterized by twoEF-hand calcium-binding motifs. There are at least 21 different S100 proteins; and the name is derived from the fact that the protein is100%soluble in ammonium sulfateat neutralpH. Most S100 proteins are disulfide-linked homodimer; and is normally present in cells derived from theneural crest; chondrocytes; macrophages; dendritic cells; etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation; transcription factors; the dynamics of cytoskeleton constituents; enzyme activities; cell growth and differentiation; and the inflammatory response. S100A6 (S100 calcium binding protein A6) is a member of the S100 family of proteins; and functions in prolactin secretion; and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma.

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