Recombinant Human S100A6 Protein (Baculovirus, His Tag)

S100 proteinis a family of low molecular weight protein found in vertebrates characterized by twoEF-hand calcium-binding motifs. There are at least 21 different S100 proteins; and the name is derived from the fact that the protein is100%soluble in ammonium sulfateat neutralpH. Most S100 proteins are disulfide-linked homodimer; and is normally present in cells derived from theneural crest; chondrocytes; macrophages; dendritic cells; etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation; transcription factors; the dynamics of cytoskeleton constituents; enzyme activities; cell growth and differentiation; and the inflammatory response. S100A6 (S100 calcium binding protein A6) is a member of the S100 family of proteins; and functions in prolactin secretion; and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma.