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Recombinant Human SELENOI/EPT1 Protein (GST Tag)

Uniprot : Q9C0D9
  • Cat.No.:PKSH032407

  • Expression host: E.coli

To Purchase PKSH032407

Size:
  • 10μg
  • 50μg
Price: $223
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Description

Synonyms Ethanolaminephosphotransferase 1;hEPT1;Selenoprotein I;SelI;EPT1;KIAA1724;SELI
Species Human
Expression_host E.coli
Sequence Met 1-Pro50
Accession Q9C0D9
Mol_Mass 32.6 kDa
AP_Mol_Mass 29 kDa
Tag N-GST

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM EDTA, pH 8.0.
Reconstitution Not Applicable

Background

Ethanolaminephosphotransferase 1 (EPT1) is an enzyme that belongs to the CDP-Alcohol Phosphatidyltransferase Class-I Family. EPT1 is a Selenoprotein, which contains a Selenocysteine (Sec) residue at its active site. The Selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of Selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. EPT1 catalyzes Phosphatidylethanolamine biosynthesis from CDP-Ethanolamine. It plays a central role in the formation and maintenance of vesicular membranes. EPT1 is involved in the formation of Phosphatidylethanolamine via the 'Kennedy' pathway.

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