Synonyms	L-selectin;CD62 antigen-like family member L;Leukocyte adhesion molecule 1;Leukocyte surface antigen Leu-8;Leukocyte-endothelial cell adhesion molecule 1;Lymph node homing receptor;TQ1;gp90-MEL;LNHR;LYAM1;CD62L;LAM1;LECAM1;LEU8;LSEL;LYAM1;PLNHR
Species	Human
Expression_host	HEK293 Cells
Sequence	Trp39-Asn332
Accession	P14151
Mol_Mass	34.0 kDa
AP_Mol_Mass	60 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

SELL contains one C-type lectin domain; one EGF-like domain and two Sushi (CCP/SCR) domains. SELL is expressed in B-cell lines and T-lymphocytes. SELL functions as a cell surface adhesion protein and mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. In addition; SELL also promotes initial tethering and rolling of leukocytes in endothelia.

Citations

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