Recombinant Human SerpinE2/SERPINE2 Protein (His Tag)

    • Recombinant Human Serpin E2 / PN1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human Serpin E2 / PN1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human Serpin E2 / PN1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033671

      Synonyms:Glia-derived Nexin; GDN; Peptidase inhibitor 7; PI-7; Protease nexin 1; PN-1; Protease nexin I; Serpin E2; SERPINE2; PI7; PN1

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $328

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Glia-derived Nexin; GDN; Peptidase inhibitor 7; PI-7; Protease nexin 1; PN-1; Protease nexin I; Serpin E2; SERPINE2; PI7; PN1
      Species Human
      Expression_host Human Cells
      Sequence Ser20-Pro397
      Accession P07093-2
      Mol_Mass 42.7 kDa
      AP_Mol_Mass 50 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH8.0.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal pancreas and chronic pancreatitis tissue. In contrast, it was strongly over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples. Serpin E2 promotes neurite extension by inhibiting thrombin. It also can bind heparin. It has been shown that Serpin E2 is a novel target of ERK signaling involved in human colorectal tumorigenesis. It plays an important role in controlling male fertility because its knockout male mice show a marked impairment in fertility from the onset of sexual maturity and its abnormal expression is found in the semen of men with seminal dysfunction.

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      MSDS for ELISA ISO 9001

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