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Current Position:Home>>Protein Products>>Recombinant Proteins>> Recombinant Human SH2D1A/SAP Protein (His Tag)

Recombinant Human SH2D1A/SAP Protein (His Tag)

  • Cat.No.:PKSH033379

  • Expression host: E.coli
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Description

Synonyms SH2 Domain-Containing Protein 1A;Duncan Disease SH2-Protein;Signaling Lymphocytic Activation Molecule-Associated Protein;SLAM-Associated Protein;T-Cell Signal Transduction Molecule SAP;SH2D1A;DSHP;EBVS;IMD5;LYP;MTCP1;SAP/SH2D1A;XLP;XLPD;XLPD1
Species Human
Expression_host E.coli
Sequence Met 1-Pro128
Accession O60880
Mol_Mass 16.4 kDa
AP_Mol_Mass 16 kDa
Tag N-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.
Reconstitution Not Applicable

Background

SH2 Domain-Containing Protein 1A,(SH2D1A) contains one SH2 domain and a short tail and is localized in the cytoplasm. SH2D1A is expressed at a high level in the thymus and the lung, with lower expression levels in the spleen and the liver. SH2D1A acts as an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. In addition, SH2D1A mediates interaction between FYN and SLAMF1. It is also thought to regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.

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