Recombinant Human SPEG / APEG-1 Protein (His tag)

    • Recombinant Human SPEG / APEG-1 Protein (His tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Human SPEG / APEG-1 Protein (His tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Human SPEG / APEG-1 Protein (His tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSH030334

      Synonyms:APEG-1;APEG1;BPEG;CNM5;SPEGalpha;SPEGbeta

      Size:
      • 50µg
      Qty:
      - +
      Price: $486

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms APEG-1;APEG1;BPEG;CNM5;SPEGalpha;SPEGbeta
      Species Human
      Expression_host E.coli
      Sequence Met 1-Glu 113
      Accession Q15772-4
      Mol_Mass 14 kDa
      AP_Mol_Mass 19 kDa
      Tag C-His

      Properties

      Purity > 85 % as determined by reducing SDS-PAGE.
      Endotoxin Please contact us for more information.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as sterile PBS, pH 7.4
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein which belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. SPEG / APEG-1 contains two fibronectin type-III domains, nine Ig-like (immunoglobulin-like) domains, two protein kinase domains. Isoform 1 of SPEG is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 of SPEG is predominantly expressed in the aorta. Isoform 3 of SPEG appears to be expressed only in highly differentiated ASMC in normal vessel walls and down-regulated in dedifferentiated ASMC. Isoform 3 of SPEG may have a role in regulating the growth and differentiation of arterial smooth muscle cells. Isoform 3 of SPEG is quickly down-regulated in response to vascular injury, when ASMC cells change from a quiescent to a proliferative phenotype.

      SDS-PAGE

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