Recombinant Human TGFB1/TGF-beta 1 Protein (His Tag)

    • Recombinant Human TGF-beta 1 / TGFB1 Protein (N-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human TGF-beta 1 / TGFB1 Protein (N-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human TGF-beta 1 / TGFB1 Protein (N-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033495

      Synonyms:Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB;CED;DPD1;TGF-beta 1

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $178

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB;CED;DPD1;TGF-beta 1
      Species Human
      Expression_host Human Cells
      Sequence Leu30-Ser390(Cys33Ser)
      Accession P01137
      Mol_Mass 41.3&12.8 kDa
      AP_Mol_Mass 38-55 kDa
      Tag N-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 50mM Glycine, 50mM NaCl, pH4.0.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.

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