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Recombinant Human TNFSF4/OX40L Protein (His Tag)(Active)

  • Cat.No.:PKSH032842

  • Expression host: Human Cells

To Purchase PKSH032842

Size:
  • 10μg
  • 50μg
Price: $178
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Description

Synonyms Tumor necrosis factor ligand superfamily member 4;Glycoprotein Gp34;OX40 ligand;OX40L;TAX transcriptionally-activated glycoprotein 1;TNFSF4;CD252;TXGP1;CD134L;CD252;GP34;OX-40;TXGP1
Species Human
Expression_host Human Cells
Sequence Gln51-Leu183
Accession P23510
Application Functional ELISA
Mol_Mass 16.3 kDa
AP_Mol_Mass 25-28 kDa
Tag N-6His
Bio_Activity Immobilized Human OX40-Fc(Cat: PKSH032844) at 2μg/ml(100 μl/well) can bind Biotinylated Human OX40L-His. The ED50 of Human OX40L-His is 4.7 ug/ml .

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per µg as determined by the LAL method.
Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.

Background

Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on the surface of activated B cells, T cells, dendritic cells and endothelial cells. OX40L binds to OX40 (CD134), a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional, it has been found association with systemic lupus erythematosus, no association with occurrence of atherosclerosis.

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