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Recombinant Human UBE2B/HR6B Protein (His Tag)

Uniprot : P63146
  • Cat.No.:PKSH033180

  • Expression host: HEK293 Cells

To Purchase PKSH033180

Size:
  • 10μg
  • 50μg
Price: $275
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Description

Synonyms Ubiquitin-Conjugating Enzyme E2 B;RAD6 Homolog B;HR6B;hHR6B;Ubiquitin Carrier Protein B;Ubiquitin-Conjugating Enzyme E2-17 kDa;Ubiquitin-Protein Ligase B;UBE2B;RAD6B
Species Human
Expression_host HEK293 Cells
Sequence Met 1-Ser152
Accession P63146
Mol_Mass 18.3 kDa
AP_Mol_Mass 17 kDa
Tag C-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution Not Applicable

Background

Ubiquitin-Conjugating Enzyme E2 B (UBE2B) is a member of the ubiquitin-conjugating enzyme family. UBE2B accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It is shown that UBE2B interacts with RAD18; UBR2; and WAC. UBE2B is required for post-replicative DNA damage repair. Additional; UBE2B plays a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.

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