Synonyms	Ubiquitin-Conjugating Enzyme E2 R2;Ubiquitin Carrier Protein R2;Ubiquitin-Conjugating Enzyme E2-CDC34B;Ubiquitin-Protein Ligase R2;UBE2R2;CDC34B;UBC3B
Species	Human
Expression_host	E.coli
Sequence	Met 1-Ser238
Accession	Q712K3
Mol_Mass	29.3 kDa
AP_Mol_Mass	37 kDa
Tag	N-His

Properties

Purity	> 90 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 50mm HEPES,150mM NaCl, pH 7.5.
Reconstitution	Not Applicable

Background

Ubiquitin-Conjugating Enzyme E2 R2 (UBE2R2) is a modification enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2R2 is involved in cell growth and transformation. It accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, UBE2R2 catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. It may be involved in degradation of katenin.

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