Recombinant Human UBE2T Protein (His Tag) (PKSH030839)
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For research use only.
| Synonyms | Cell Proliferation-Inducing Gene 50 Protein, UBE2T, Ubiquitin Carrier Protein T, Ubiquitin-Conjugating Enzyme E2 T, Ubiquitin-Protein Ligase T |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Val197 |
| Accession | Q9NPD8 |
| Calculated Molecular Weight | 23.9 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Form | Liquid |
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as sterile PBS, 30 % glycerol, 0.1 % Tween 20, 0.4 mM Chaps, pH 7.5. |
| Background | Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers; representing an attractive target for the development of inhibitors. Notably; UBE2T locates at 1q32.1; and the gain of 1q is frequently observed in a variety of cancers. For instance; UBE2T serves an important role in the growth of bladder cancer cells; and may be considered as a potential biomarker and therapeutic target for bladder cancer. |
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