Recombinant Human Vaspin/SerpinA12 Protein (His Tag)

    • Recombinant Human Vaspin / Serpin A12 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human Vaspin / Serpin A12 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human Vaspin / Serpin A12 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033533

      Synonyms:Serpin A12; OL-64; Visceral adipose tissue-derived serine protease inhibitor; Vaspin; Visceral adipose-specific serpin; SERPINA12

      Size:
      • 10μg
      • 50μg
      Qty:
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      Price: $275

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      Overview

      Synonyms Serpin A12; OL-64; Visceral adipose tissue-derived serine protease inhibitor; Vaspin; Visceral adipose-specific serpin; SERPINA12
      Species Human
      Expression_host Human Cells
      Sequence Leu21-Lys414
      Accession Q8IW75
      Mol_Mass 46.5 kDa
      AP_Mol_Mass 50-60 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH7.5.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.

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