Recombinant Mouse β-NGF/Beta-NGF Protein (Active)

    • Recombinant Mouse β-NGF / Beta-NGF Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Mouse β-NGF / Beta-NGF Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Mouse β-NGF / Beta-NGF Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSM040709

      Synonyms:Ngfb

      Size:
      • 5 μg
      • 20 μg
      Qty:
      - +
      Price: $127

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms Ngfb
      Species Mouse
      Expression_host CHO Stable Cells
      Sequence Ser 122-Gly 241
      Accession NP_001106168.1
      Application Cell Culture
      Mol_Mass 13.5 kDa
      AP_Mol_Mass 13.5 kDa
      Bio_Activity Measured in a cell proliferation assay using TF-1 human erythroleukemic cells.The ED50 for this effect is 1-8ng/mL.

      Properties

      Purity > 96 % as determined by SDS-PAGE
      Endotoxin < 1.0 EU per µg of the protein as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile 20mM NaAc, 150mM NaCl, pH 5.5
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. In addition, previous studies indicated that NGF may also have an important role in the regulation of the immune system.

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