Recombinant Mouse CD112/Nectin-2 Protein (His Tag)(Active)

    • Recombinant Mouse  Nectin-2 Protein (His Tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Mouse  Nectin-2 Protein (His Tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Mouse  Nectin-2 Protein (His Tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSM040739

      Synonyms:AI325026 Protein, AI987993 Protein, Cd112 Protein, MPH Protein, nectin-2 Protein, Pvr Protein, Pvs Protein

      Size:
      • 50 μg
      • 100 μg
      Qty:
      - +
      Price: $454

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms AI325026 Protein, AI987993 Protein, Cd112 Protein, MPH Protein, nectin-2 Protein, Pvr Protein, Pvs Protein
      Species Mouse
      Expression_host HEK293 Cells
      Sequence Met 1-Gly 351
      Accession NP_033016.3
      Application Functional ELISA
      Mol_Mass 36 kDa
      AP_Mol_Mass 40-45 kDa
      Tag C-His
      Bio_Activity Measured by its binding ability in a functional ELISA.1. Immobilized mouse CD112-His at 10 µg/ml (100 μl/well) can bind biotinylated mouse DNAM1-His with a linear range of 0.156-5.0 µg/ml.2. Immobilized mouse CD112-His at 10 µg/ml (100 μl/well) can bind

      Properties

      Purity > 98 % as determined by SDS-PAGE
      Endotoxin < 1.0 EU per µg of the protein as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile PBS, pH 7.4
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+ T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy.

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      MSDS for ELISA ISO 9001

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