Recombinant Mouse CD40/TNFRSF5 Protein (His Tag)(Active)

    • Recombinant Mouse CD40 / TNFRSF5 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Mouse CD40 / TNFRSF5 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Mouse CD40 / TNFRSF5 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSM041263

      Synonyms:Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CD40; TNFRSF5;I326936;HIGM1; IGM; IMD3; p50; T-BAM; Tnfrsf5; TRAP

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $117

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      Overview

      Synonyms Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CD40; TNFRSF5;I326936;HIGM1; IGM; IMD3; p50; T-BAM; Tnfrsf5; TRAP
      Species Mouse
      Expression_host Human Cells
      Sequence Leu20-Arg193
      Accession P27512
      Application Functional ELISA
      Mol_Mass 20.2 kDa
      AP_Mol_Mass 21-25 kDa
      Tag C-His
      Bio_Activity Immobilized Human CD40L(Cat: PKSH033725) at 5μg/ml(100 μl/well) can bind Mouse CD40-6His.

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction. CD40 plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.

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      MSDS for ELISA ISO 9001

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