Recombinant Mouse CXADR/CAR Protein (Fc Tag)

    • Recombinant Mouse CXADR / CAR Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Mouse CXADR / CAR Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Mouse CXADR / CAR Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSM041345

      Synonyms:Coxsackievirus and adenovirus receptor homolog;CAR;Cxadr;CVB3 BP;MCVADR

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $129

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Coxsackievirus and adenovirus receptor homolog;CAR;Cxadr;CVB3 BP;MCVADR
      Species Mouse
      Expression_host Human Cells
      Sequence Leu20-Gly237
      Accession P97792
      Mol_Mass 51 kDa
      AP_Mol_Mass 50-70 kDa
      Tag C-Fc

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Coxsackievirus and adenovirus receptor homolog(CAR), also known as CXADR, is a type I transmembrane glycoprotein that belongs to the CTX family of the Ig superfamily. CXADR has monomer subunit that interacts with LNX, BAIAP1, DLG4, PRKCABP, TJP1 and CTNNB1. It also interacts with MPDZ and JAML. CXADR composed of of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. CXADR also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

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      MSDS for ELISA ISO 9001

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