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Recombinant Mouse CXCL10 protein(His Tag)

Uniprot : P17515
  • Cat.No.:PKSM041503

  • Expression host: E.coli

To Purchase PKSM041503

Size:
  • 20μg
  • 100μg
Price: $249
Qty:

Description

Synonyms IFNB1;Type I Interferon
Species Mouse
Expression_host E.coli
Sequence Ile 22-Pro 98
Accession P17515
Mol_Mass 9.5 kDa
AP_Mol_Mass 11-17 kDa
Tag N-His
Bio_Activity Measure by its ability to chemoattract BaF3 cells transfected with human CXCR3.The ED50 for this effect is <0.2 μg/mL.

Properties

Purity > 98 % as determined by reducing SDS-PAGE.
Endotoxin level < 0.1 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.

Background

Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types; such as monocytes; endothelial cells and fibroblasts; in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles; such as chemoattraction for activated T-lymphocytes; inhibition of angiogenesis; and antitumor activity.

Citations

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