Click here to view cell apoptosis assay products
×

Recombinant Mouse EpCAM/TROP-1 Protein (Fc Tag)(Active)

Uniprot : Q99JW5
  • Cat.No.:PKSM041339

  • Expression host: Human Cells

To Purchase PKSM041339

Size:
  • 10µg
  • 50µg
Price: $62
Qty:

Description

Synonyms Neurotrophic tyrosine kinase receptor-related 1; receptor tyrosine kinase-like orphan receptor 1; ROR1;tyrosine-protein kinase transmembrane receptor ROR1; Epithelial cell adhesion molecule; Tumor-associated calcium signal transducer 1;TROP1;CD326;EGP;EGP-2;Egp314;Ep-CAM;EpCAM1;GA733-2;gp40;Ly74;Tacsd1;Tacstd1
Species Mouse
Expression_host Human Cells
Sequence Gln24-Thr266
Accession Q99JW5
Application Functional ELISA
Mol_Mass 54.8 kDa
AP_Mol_Mass 60-80 kDa
Tag C-Fc
Bio_Activity Immobilized Human CTSL2-His(Cat: PKSH032183) at 10μg/ml(100 μl/well) can bind Mouse EpCAM-Fc.

Properties

Purity > 95% as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg as determined by the LAL method.
Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.

Background

ROR1,also known as Neurotrophic tyrosine kinase, receptor-related 1, belongs to the ROR subfamily of Tyr protein kinase family,a protein kinase superfamily. It has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Human ROR1 is a type I transmembrane protein with 937 amino acids (aa) in length. It contains a 29 aa signal sequence, a 377 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 510 aa cytoplasmic region. Human ROR1 shares 97% and 58% aa sequence identity with mouse ROR1 and human ROR2, respectively. ROR1 may act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling. ROR1 expressed strongly in human heart, lung and kidney, but weakly in the CNS. Its Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm.

Related Products

Citations

From now on, if you have published a paper by using any of our products since 1/1/2019, fill out the “Elabscience Publication Reward Application Form”carefully and send it to orders@elabscience.com, we will get back to you with the reward after we confirm it ASAP!

View more details about our Publication Reward >>

Reviews/Q&A

  • Show all
  • Reviews
  • Q&A
... Show All Show Less

People Also Bought

Apply for
*Product Name:
*Catalog Number:
*Name:
*Email:
*Message:
*Country:
*When will you use it?

*Captcha: