Recombinant Mouse IGF1(Long-R3-IGF1) Protein (His Tag)(Active)

    • Recombinant Mouse IGF1(Long-R3-IGF1) Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Mouse IGF1(Long-R3-IGF1) Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Mouse IGF1(Long-R3-IGF1) Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSM041325

      Synonyms:IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I;Somatomedin C; somatomedin-C

      Size:
      • 10μg
      • 50μg
      Qty:
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      Price: $37

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      Overview

      Synonyms IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I;Somatomedin C; somatomedin-C
      Species Mouse
      Expression_host E.coli
      Sequence Gly49-Ala118
      Accession P05017
      Application Cell Culture
      Mol_Mass 10.2 kDa
      AP_Mol_Mass 12 kDa
      Tag C-His
      Bio_Activity Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells.  The ED50 for this effect is 842 ng/ml.

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 20mM NaAc, pH 4.5.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors.

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      MSDS for ELISA ISO 9001

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