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Recombinant Mouse IL2Ra/CD25 Protein (Fc Tag)

  • Cat.No.:PKSM041228

  • Expression host: HEK293 Cells
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Description

Synonyms CD25;IL-2 R alpha;IL2RA;CD25 antigen;IDDM10;IL-2 receptor subunit alpha;IL2R;IL-2R subunit alpha;IL-2-RA;IL2-RA;interleukin 2 receptor;alpha;interleukin-2 receptor subunit alpha;p55;TAC antigen;TCGFR;Il2r;Ly-43
Species Mouse
Expression_host HEK293 Cells
Sequence Glu22-Lys236
Accession P01590
Mol_Mass 51.6 kDa
AP_Mol_Mass 60-90 kDa
Tag C-Fc

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.

Background

The interleukin 2 receptor alpha (IL2RA), also called CD25, is a type I transmembrane protein that presents on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. IL2RA is a member of cytokine receptors family that utilizes the common gamma chain subunit (γc). IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. IL2RA associates with IL2RB (CD122) to form a heterodimer that can act as a high-affinity receptor for IL-2.

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