Recombinant Mouse IL-2 Receptor Subunit Beta/IL-2RB/CD122 (C-6His) (PKSM041436)
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For research use only.
| Synonyms | beta, CD122, High affinity IL-2 receptor subunit beta, IL-15Rbeta, IL-2 receptor subunit beta, Il-2/15Rbeta, IL-2R subunit beta, IL-2R&, IL-2RB, Il-2Rbeta, IL15RB, IL15Rbeta, Il2rb, Interleukin-15 receptor subunit beta, Interleukin-2 receptor subunit beta, p70, p70-75, p75 |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Ala27-Glu240 |
| Accession | P16297 |
| Calculated Molecular Weight | 26.1 kDa |
| Observed Molecular Weight | 40-60 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Form | Lyophilized powder |
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, 8% Trehalose, 4% Mannitol, 0.05% Tween 80, pH7.4. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Background | IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs. |
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