Recombinant Mouse MMP8/CLG1 Protein

    • Recombinant Mouse MMP-8 / CLG1 Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Mouse MMP-8 / CLG1 Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Mouse MMP-8 / CLG1 Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSM040651

      Synonyms:BB138268

      Size:
      • 10 μg
      • 20 μg
      Qty:
      - +
      Price: $454

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms BB138268
      Species Mouse
      Expression_host HEK293 Cells
      Sequence Phe 21-Ser 465
      Accession NP_032637.3
      Mol_Mass 52 kDa
      AP_Mol_Mass 65 kDa

      Properties

      Purity > 85 % as determined by SDS-PAGE
      Endotoxin < 1.0 EU per µg of the protein as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile PBS, pH 7.4
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases and tumor invasion. Neutrophil collagenase, also known as Matrix metalloproteinase-8, MMP-8, and CLG1, is a member of the peptidase M10A family. MMP-8 may affect the metastatic behaviour of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumour may have a protective effect against lymph node metastasis. MMP-8 may affect the metastatic behaviour of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 participates in wound repair by contributing to the resolution of inflammation and open the possibility to develop new strategies for treating wound healing defects.

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