Recombinant Mouse Myeloperoxidase/MPO Protein (His Tag)

    • Recombinant Mouse Myeloperoxidase / MPO Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Mouse Myeloperoxidase / MPO Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Mouse Myeloperoxidase / MPO Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSM041302

      Synonyms:Myeloperoxidase; MPO

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $129

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Myeloperoxidase; MPO
      Species Mouse
      Expression_host Human Cells
      Sequence Met16-Thr718
      Accession P11247
      Mol_Mass 81.1 kDa
      AP_Mol_Mass 93 kDa
      Tag C-His

      Properties

      Purity > 90% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Myeloperoxidase (MPO) is a hemecontaining enzyme belonging to the XPO subfamily of peroxidases. It is an abundant neutrophil and monocyte glycoprotein that catalyzes the hydrogen peroxidedependent conversion of chloride, bromide, and iodide to multiple reactive species. MPO activity results in protein nitrosylation and the formation of 3-chlorotyrosine and dityrosine crosslinks. Modification of ApoB100, as well as the lipid and cholesterol components of LDL and HDL, promotes the development of atherosclerosis. MPO is also associated with a variety of other diseases, and inhibits vasodilation in inflammation by depleting the levels of NO. Serum albumin functions as a carrier protein during MPO movement to the basolateral side of epithelial cells. MPO is stored in neutrophil azurophilic granules. Upon cellular activation, it is deposited into pathogencontaining phagosomes. While mice lacking MPO are impaired in clearing select microbial infections,MPO deficiency in humans does not necessarily result in heightened susceptibility to infections.

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      MSDS for ELISA ISO 9001

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