Recombinant Mouse Podoplanin/PDPN Protein (His Tag)

    • Recombinant Mouse Podoplanin / PDPN Protein (His tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Mouse Podoplanin / PDPN Protein (His tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Mouse Podoplanin / PDPN Protein (His tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSM040776

      Synonyms:Gp38;OTS-8;RANDAM-2;T1-alpha;T1a;T1alpha;Podoplanin; Aggrus; Glycoprotein 38; PA2.26 antigen

      Size:
      • 50 μg
      • 100 μg
      Qty:
      - +
      Price: $454

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms Gp38;OTS-8;RANDAM-2;T1-alpha;T1a;T1alpha;Podoplanin; Aggrus; Glycoprotein 38; PA2.26 antigen
      Species Mouse
      Expression_host Baculovirus-Insect Cells
      Sequence Met 1-Lys 133
      Accession NP_034459.2
      Mol_Mass 13 kDa
      AP_Mol_Mass 25 kDa
      Tag C-His

      Properties

      Purity > 92 % as determined by SDS-PAGE
      Endotoxin < 1.0 EU per µg of the protein as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Podoplanin, also known as PDPN, is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined. Alternatively spliced transcript variants encoding different isoforms have been identified.PDPN is a mucin-type glycoprotein negatively charged by extensive O-glycosylation and a high content of sialic acid, which expresses the adhesive property. It is selectively expressed in lymphatic endothelium as well as lymphangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. PDPN may contribute to form odontoblastic fiber or function as the anchorage to the tooth development and in proliferating epithelial cells of cervical loop and apical bud. The intensity of podoplanin expression is negatively correlated with the expression of CD34 and factor VIII. Podoplanin would be useful as a diagnostic marker for epithelioid hemangioendothelioma in liver tumors.

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      MSDS for ELISA ISO 9001

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