Recombinant Mouse S100A11 Protein (His Tag)(Active)

    • Recombinant Mouse S100A11 Protein (N-His)-Elabscience
    • Recombinant Protein-Elabscience
    <
    >
    • Recombinant Mouse S100A11 Protein (N-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Mouse S100A11 Protein (N-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSM041286

      Synonyms:Protein S100-A11; Calgizzarin; Endothelial monocyte-activating polypeptide; EMAP; Protein S100-C; S100 calcium-binding protein A11; S100a11; S100c;cal;Emap1;EMAPI;S100A11;S100a14;S100c

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $62

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms Protein S100-A11; Calgizzarin; Endothelial monocyte-activating polypeptide; EMAP; Protein S100-C; S100 calcium-binding protein A11; S100a11; S100c;cal;Emap1;EMAPI;S100A11;S100a14;S100c
      Species Mouse
      Expression_host E.coli
      Sequence Met1-Ile98
      Accession P50543
      Application Functional ELISA
      Mol_Mass 12.6 kDa
      AP_Mol_Mass 12 kDa
      Tag N-His
      Bio_Activity Immobilized Human ANXA2(Cat: PKSH032074) at 10μg/ml(100 μl/well) can bind Mouse S100A11-His. The ED50 of Mouse S100A11-His is 0.8μg/mL.

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Protein S100-A11(S100A11) is a member of the S-100 family. S100A11 is widely expressed in multi pletissues, and is located in cytoplasm, nucleus, and even cell periphery. S100A11 exists as a non-covalent homodimer with an antiparallel conformation. Ca(2+) binding to S100A11 would trigger conformational changes which would expose the hydrophobic cleft of S100A11 and facilitate its interaction with target proteins. As a dual cell growth mediator, S100A11 acts as either a tumor suppressor or promoter in many different types of tumors and would play respective roles in influencing the proliferatin of the cancer cells. In the nucleus, S100A11 suppresses the growth of keratinocytes through p21 (CIP1/WAF1) activation and induces cell differentiation. S100A11 is also a novel diagnostic marker in breast carcinoma.

      Image

      submit review
      • Show all (0)
      • Reviews (0)
      • Q&A (0)
      ... Show All Show Less
      MSDS for ELISA ISO 9001

      Browsing History


        People Also Bought

        Apply for Free Shipping 24T ELISA Kit
        *Product Name:
        *Catalog Number:
        Size:
        *Name:
        *Email:
        *Phone:
        *Message:
        *Country:
        How do you know
        Elabscience:

        *Verification code: