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Recombinant Mouse Serpin F1/PEDF Protein

  • Cat.No.:PKSM041232

  • Expression host: E.coli
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Description

Synonyms Pigment epithelium-derived factor;Pedf;Sdf3;Caspin;Serpin F1;Stromal cell-derived factor 3.
Species Mouse
Expression_host E.coli
Sequence Asp43-Thr417
Accession P97298
Mol_Mass 42.0 kDa
AP_Mol_Mass 40 kDa
Tag None

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution Not Applicable

Background

Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. It induces extensive neuronal differentiation in retinoblastoma cells. It is potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, exhibits no serine protease inhibitory activity.

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