Recombinant Mouse SerpinE2/SERPINE2 Protein (His Tag)

    • Recombinant Mouse Serpin E2 / PN1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Mouse Serpin E2 / PN1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Mouse Serpin E2 / PN1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSM041335

      Synonyms:Glia-derived nexin; GDN; Peptidase inhibitor 7; PI-7; Protease nexin 1; PN-1; Protease nexin I; Serine protease-inhibitor 4; Serpin E2; Pi7; Pn1; Spi4

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $245

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Glia-derived nexin; GDN; Peptidase inhibitor 7; PI-7; Protease nexin 1; PN-1; Protease nexin I; Serine protease-inhibitor 4; Serpin E2; Pi7; Pn1; Spi4
      Species Mouse
      Expression_host Human Cells
      Sequence Ser20-Pro397
      Accession Q07235
      Mol_Mass 43.2 kDa
      AP_Mol_Mass 50-55 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris,150 mM NaCl,pH8.0.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Serpin E2 is a member of the Serpin superfamily of the serine protease inhibitors. Serpin E2 is apotent inhibitor of thrombin, plasmin and plasminogen activators. It is differentially expressed during neuronal differentiation and is able to transform humanembryonic kidney cells into neuronlikecells. Its over-expressionin mice leads to progressive neuronal and motor dysfunction in these animals. It is also over-expressedin the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples whereas it is weakly expressed in all normal pancreas and chronicpancreatitis tissue samples. It plays an important role in controlling male fertility because its knockout male mice show a marked impairment in fertility from theonset of sexual maturity and its abnormal expression is found in the semen of men with seminal dysfunction.

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      MSDS for ELISA ISO 9001

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