Recombinant Mouse TNFR1/TNFRSF1A Protein (Fc Tag)(Active)

    • Recombinant Mouse TNFR1 / CD120a / TNFRSF1A Protein (Fc tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Mouse TNFR1 / CD120a / TNFRSF1A Protein (Fc tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Mouse TNFR1 / CD120a / TNFRSF1A Protein (Fc tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSM040649

      Synonyms:CD120a;FPF;p55;p55-R;TNF-alphaR1;TNF-R;TNF-R-I;TNF-R1;TNF-R55;TNFalpha-R1;TNFAR;Tnfr-2;Tnfr1;TNFR60;TNFRI;TNFRp55

      Size:
      • 50 μg
      • 100 μg
      Qty:
      - +
      Price: $454

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms CD120a;FPF;p55;p55-R;TNF-alphaR1;TNF-R;TNF-R-I;TNF-R1;TNF-R55;TNFalpha-R1;TNFAR;Tnfr-2;Tnfr1;TNFR60;TNFRI;TNFRp55
      Species Mouse
      Expression_host HEK293 Cells
      Sequence Met 1-Ala 212
      Accession NP_ 035739.2
      Application Functional ELISA
      Mol_Mass 47.4 kDa
      AP_Mol_Mass 55 kDa
      Tag C-Fc
      Bio_Activity Immobilized mouse TNFa (80-235) at 10 µg/ml (100 μl/well) can bind mouse TNFRSF1A-Fc, The EC50 of mouse TNFRSF1A-Fc is 0.03-0.07 µg/ml.

      Properties

      Purity > 90 % as determined by SDS-PAGE
      Endotoxin < 1.0 EU per µg of the protein as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile PBS, pH 7.4
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.

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      MSDS for ELISA ISO 9001

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