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Recombinant Mouse VCAM1 Protein (Fc Tag)

  • Cat.No.:PKSM041260

  • Expression host: Human Cells

To Purchase PKSM041260

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  • 10μg
  • 50μg
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Description

Synonyms CD106;Vascular cell adhesion protein 1; Vcam1; L1CAM;VCMA1;Vcam-1
Species Mouse
Expression_host Human Cells
Sequence Phe25-Glu698
Accession P29533
Mol_Mass 101.4 kDa
AP_Mol_Mass 130 kDa
Tag C-Fc

Properties

Purity > 90% as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg as determined by the LAL method.
Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.

Background

Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily, the protein is expressed by activated endothelial cells and certain leukocytes (such as macrophages). IL-1 beta, IL-4, TNF-alpha and IFN-gamma induced the expression of VCAM-1. The human and mouse VCAM-1 proteins share approximately 76% amino acid similarity. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction.

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